IN VITRO PRODUCTION OF ANDROGENS BY A VIRILIZING ADRENAL ADENOMA AND ASSOCIATED POLYCYSTIC OVARIES
- 1 September 1963
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 44 (1) , 15-19
- https://doi.org/10.1530/acta.0.0440015
Abstract
A case of a virilizing adrenal adenoma in which bilateral Stein-Leventhal ovaries were found is presented. Despite the morphologic similarity, these ovaries did not possess the in vitro potential for increased androgen production demonstrated by polycystic ovaries removed from patients without apparent adrenal disease. These findings lend support to the thesis that, regardless of the organ source, increased androgen production leads to abnormal ovarian function reflected morphologically in follicle maturation arrest.Keywords
This publication has 3 references indexed in Scilit:
- The Polycystic Ovary. III. Steroid Biosynthesis in Normal and Polycystic Ovarian Tissue1Journal of Clinical Endocrinology & Metabolism, 1962
- The Polycystic Ovary. I. Clinical and Histologic FeaturesJournal of Clinical Endocrinology & Metabolism, 1962
- BIOGENESIS OF ESTROGENS BY THE HUMAN OVARY:1FORMATION OF NETURAL STEROID INTERMEDIATES FROM PROGESTERONE-4-C14, ANDROSTENEDIONE-4-C14AND CHOLESTEROL-4-C141Endocrinology, 1961