The distribution of phospholipase B in mammalian tissues

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Abstract
A study was made of the distribution of phospholipase B in certain mammalian tissues, by using whole homogenates of the different tissues. Enzymic activity was estimated by determining the rate of release of both free fatty acids and glycerylphosphorylcholine. The properties of the enzyme in whole rat liver homogenates agree closely with those described by Dawson (1956) in glycerol extracts of acetone-dried preparations of this tissue. High levels of activity were found in ileum, lung, spleen, liver and pancreas. The activity was low in skeletal muscle, heart muscle, kidney, testis, brain and blood. The gray matter of the central nervous system contains considerably more activity than the white matter.