Yeast-Mediated Reduction of N-Substituted Acetoacetamides. Improvement of Conversion by Immobilization
- 1 August 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 61 (8) , 3014-3016
- https://doi.org/10.1246/bcsj.61.3014
Abstract
N-Ethylacetoacetamide and acetoacetanilide were enantioselectively converted into the corresponding (S)-3-hydroxy compounds by alginate- or polyurethaneimmobilized bakers’ yeasts, while without immobilization the yield of the yeast-mediated reaction was very low.Keywords
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