Brief Communication: Accelerated Development of Benzo [ a ] pyrene-Induced Skin Tumors in Mice Treated With Pyran Copolymer 2
- 1 November 1974
- journal article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 53 (5) , 1409-1410
- https://doi.org/10.1093/jnci/53.5.1409
Abstract
Chronic treatment of C3H mice with pyran, a copolymer of maleic anhydride and divinyl ether, markedly accelerated the induction of skin tumors by benzo[a]pyrene. Thirty weeks after the initiation of pyran and carcinogen treatment, 85% of the animals had developed skin tumors; at the same time, tumor incidence in control mice was only 24%.Keywords
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