Loss of myostatin (GDF8) function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading
- 1 June 2007
- Vol. 40 (6) , 1544-1553
- https://doi.org/10.1016/j.bone.2007.02.012
Abstract
No abstract availableKeywords
This publication has 48 references indexed in Scilit:
- Age-related loss of muscle mass and bone strength in mice is associated with a decline in physical activity and serum leptinBone, 2006
- Increased Muscle Mass With Myostatin Deficiency Improves Gains in Bone Strength With ExerciseJournal of Bone and Mineral Research, 2006
- Myostatin Mutation Associated with Gross Muscle Hypertrophy in a ChildNew England Journal of Medicine, 2004
- The ‘muscle-bone unit’ during the pubertal growth spurtBone, 2004
- Increased bone mineral density in the femora of GDF8 knockout miceThe Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology, 2003
- Transforming Growth Factor β2 Inhibits Adipocyte Differentiation Induced by Skeletal Unloading in Rat Bone Marrow StromaJournal of Bone and Mineral Research, 2002
- Inhibition of Preadipocyte Differentiation by Myostatin Treatment in 3T3-L1 CulturesBiochemical and Biophysical Research Communications, 2001
- Regulation of skeletal muscle mass in mice by a new TGF-p superfamily memberNature, 1997
- Relationship between quadriceps strength and bone mineral density of the proximal tibia and distal forearm in womenJournal of Bone and Mineral Research, 1993
- Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committeeJournal of Bone and Mineral Research, 1987