Cellulolytic fungi were evaluated for their ability to use wheat bran and produce extracellular enzymes capable of solubilizing carbohydrate and protein fractions from wheat bran. Trichurus cylindricus grew better than all other organisms tested and excreted an extracellular enzyme system which was distinguished by high C1 and Cx cellulase and proteolytic activity. Evidence was also obtained for the existence of a partially extracellular lignolytic enzyme system. The extracellular enzyme system possessed high activity towards wheat bran and the dilute enzyme was able to bring about a 28% weight loss from the insoluble fraction of the wheat bran substrate in 24 h. The extracellular enzyme system from Trichoderma viride and Myrothecium verrucaria were also studied but they were found to be inferior to those of Trichurus cylindricus for the solubilization of wheat bran. However, the crude enzyme preparation from Trichurus cylindricus had a lower activity towards purified cellulose than the enzyme from Trichoderma viride.