Gastrin
- 19 June 1975
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 292 (25) , 1324-1334
- https://doi.org/10.1056/nejm197506192922505
Abstract
(First of Two Parts)Chemistry and PhysiologyHistoricalWHEN Bayliss and Starling1 discovered secretin in 1902, they quickly saw that they had uncovered not just a new substance but a new concept with broad biologic implications. They regarded secretin as a prototype of an entire system of "chemical messengers" that share with the nervous system the task of co-ordinating the activities of the whole body. Both systems provide mechanisms whereby stimuli received at one part of the body can control the activity of a distant part. In their first paper on secretin, Bayliss and Starling1 suggested gastric secretion as an . . .Keywords
This publication has 60 references indexed in Scilit:
- Pure human minigastrin: secretory potency and disappearance rateGut, 1974
- pH-dependent conformational change of gastrinNature, 1974
- Extraction of circulating endogenous gastrin by the gastric fundusGut, 1974
- Inactivation of pentagastrin by the liverBritish Journal of Surgery, 1974
- Enzymatic deamidation of the C-terminal tetrapeptide amide of gastrin by mammalian tissuesBiochemical Medicine, 1973
- Gastrin in portal and peripheral venous blood after feeding in manGut, 1973
- Mechanism of Inactivation of Vasopressin and Oxytocin by the Isolated Perfused Rat Kidney*Endocrinology, 1973
- The Genesis of Lower Esophageal Sphincter Pressure: Its Identification through the Use of Gastrin AntiserumJournal of Clinical Investigation, 1972
- Effect of food on serum gastrin evaluated by radioimmunoassayGut, 1971
- Stimulation of Gastric Acid Secretion by Irrigation of the Antrum with Some Aliphatic Alcohols1Acta Physiologica Scandinavica, 1969