Three-point linkage analysis employing C3 and 19cen markers assigns the myotonic dystrophy gene to 19q
- 1 March 1987
- journal article
- conference paper
- Published by Springer Nature in Human Genetics
- Vol. 75 (3) , 291-293
- https://doi.org/10.1007/bf00281077
Abstract
In seven large families with myotonic dystrophy (DM) comprising 102 individuals, linkage studies were perfermed employing restriction fragment length polymorphisms in the complement component 3 gene and the 19cen C banding heteromorphism as genetic markers. Three-point linkage analysis excludes DM from the 19cen-C3 segment and strongly supports its assignment to the proximal long arm of chromosome 19.This publication has 11 references indexed in Scilit:
- Centromere heteromorphism in chromosome 19Clinical Genetics, 2008
- RFLPs at the D19S19 locus of human chromosome 19 linked to myotonic dystrophy (DM)Nucleic Acids Research, 1986
- Toward early diagnosis of myotonic dystrophy:construction and characterization of a somatic cell hybrid with a single human der(19) chromosomeCytogenetic and Genome Research, 1986
- Report of the committee on the genetic constitution of chromosomes 17, 18 and 19Cytogenetic and Genome Research, 1985
- Abstracts of workshop presentations (Part 11 of 13)Cytogenetic and Genome Research, 1985
- TOWARD A COMPLETE LINKAGE MAP OF THE HUMAN CHROMOSOME-X - REGIONAL ASSIGNMENT OF 16 CLONED SINGLE-COPY DNA-SEQUENCES EMPLOYING A PANEL OF SOMATIC-CELL HYBRIDS1984
- Gentics and linkage relationships of the C3 polymorphism: discovery of C3‐Se linkage and assignment of LES‐C3‐DM‐Se‐PEPD‐Lu synteny to chromosome 19Clinical Genetics, 1983
- Genetic linkage between the loci for myotonic dystrophy and peptidase DAnnals of Human Genetics, 1983
- Confirmation of linkage of the loci for myotonic dystrophy and ABH secretion.Journal of Medical Genetics, 1971
- ESTIMATION OF LINKAGE BETWEEN THE LUTHERAN AND THE LEWIS BLOOD GROUPSActa Pathologica Microbiologica Scandinavica, 1951