Metabolie Conversions of Trichothecene Mycotoxins: Biotransformation of 3-AcetyldeoxynivaIenoI into Fusarenon-X
Open Access
- 1 October 1986
- journal article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung C
- Vol. 41 (9-10) , 845-850
- https://doi.org/10.1515/znc-1986-9-1008
Abstract
The trichothecene mycotoxin 3-acetyldeoxynivalenol was transformed by cultures of the diace- toxyscirpenol producer Fusarium sp. strain C37410-90 into four compounds, identified as deoxy- nivalenol, 15-acetyldeoxynivalenol, 3,15-diacetyldeoxynivalenol and fusarenon-X. The major transformations are the result of specific esterification and de-esterification processes, but the production of fusarenon-X involves in addition a novel 4p-hydroxylation of the trichothecene ring system itself.Keywords
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