Depression and CD4 Cell Count Among Persons with HIV Infection in Uganda
- 27 June 2006
- journal article
- research article
- Published by Springer Nature in AIDS and Behavior
- Vol. 10 (S1) , 105-111
- https://doi.org/10.1007/s10461-006-9142-2
Abstract
Despite the importance of mental illness and the high prevalence of HIV in Africa, few studies have documented depressive symptoms among HIV-infected persons in Africa. We assessed factors associated with depression among HIV-infected adults undergoing anti-retroviral eligibility screening in Eastern Uganda. Depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale (CES-D). Univariate and multiple regression analyses were conducted to identify socio-demographic characteristics and disease-related factors associated with depression. Among 1017 HIV-infected participants assessed for depression, 47% (476/1017) reported depressive symptoms (CES-D ≥ 23). Adjusting for age, gender, education, and source of income, patients with CD4 counts 50 years, and those without an income source were more likely to be depressed. Depression was common among HIV-infected persons in rural Uganda and was associated with low CD4 cell counts. Appropriate screening and treatment for depression should be considered for comprehensive HIV care.Keywords
This publication has 28 references indexed in Scilit:
- Changes in sexual behavior and risk of HIV transmission after antiretroviral therapy and prevention interventions in rural UgandaAIDS, 2006
- The Center for Epidemiologic Studies Depression Scale in older Chinese: thresholds for long and short formsInternational Journal of Geriatric Psychiatry, 2005
- Depressive Symptoms and AIDS-Related Mortality Among a Multisite Cohort of HIV-Positive WomenAmerican Journal of Public Health, 2004
- Assessment of depression prevalence in rural Uganda using symptom and function criteriaSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 2004
- Group Interpersonal Psychotherapy for Depression in Rural UgandaJAMA, 2003
- Meta-Analysis of the Relationship Between HIV Infection and Risk for Depressive DisordersAmerican Journal of Psychiatry, 2001
- Mortality, CD4 Cell Count Decline, and Depressive Symptoms Among HIV-Seropositive WomenJAMA, 2001
- Distinguishing between Overlapping Somatic Symptoms of Depression and HIV Disease in People Living with HIV-AIDSJournal of Nervous & Mental Disease, 2000
- Progression to AIDSPsychosomatic Medicine, 1999
- Depressive symptoms, major depression, and generalized anxiety: A comparison of self-reports on CES-D and results from diagnostic interviewsPsychiatry Research, 1985