IMMUNOLOGICAL MYOPATHY

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  • 1 January 1977
    • journal article
    • research article
    • Vol. 101  (7) , 362-365
Abstract
The histopathologic characteristics of a patient with progressive myopathy, renal failure, hemoptysis and a fulminant terminal event demonstrated a diffuse vasculitis, type 2 fiber atrophy of muscle and linear Ig[immunoglobulin]G staining of the basement membranes of skeletal muscle fibers and of glomerular capillary basement membranes. Interpretation of electron micrographs confirmed that there was thickening of muscle basement membranes. The data suggest the presence of an antibody to a basement membrane antigen shared by muscle and kidney.

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