SAMPLING VARIANCES OF HETEROZYGOSITY AND GENETIC DISTANCE
Open Access
- 1 February 1974
- journal article
- research article
- Published by Oxford University Press (OUP) in Genetics
- Vol. 76 (2) , 379-390
- https://doi.org/10.1093/genetics/76.2.379
Abstract
Mathematical formulae for the sampling variances of average heterozygosity and Nei's genetic distance are developed. These sampling variances are decomposed into their two components, i.e. the inter-locus and intra-locus variances. The relationship between the number of loci and the number of individuals per locus to be examined for estimating average heterozygosity and genetic distance is also discussed. The utility of the inter-locus variance of heterozygosity for studying the mechanism of maintenance of genetic variability in populations is indicated.Keywords
This publication has 3 references indexed in Scilit:
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- Phylogenetic analysis. Models and estimation procedures.1967
- Comparison of genetical and morphological methods for a study of biological differencesAmerican Journal of Physical Anthropology, 1953