OXIDATIVE DEAMINATION OF C-14 PUTRESCINE IN MOUSE-TISSUES INVIVO

  • 1 January 1980
    • journal article
    • research article
    • Vol. 28  (6) , 907-910
Abstract
Oxidative deamination of 14C putrescine was examined in vivo in mice. Exogenous putrescine is catabolized rapidly; 2.5 min after i.v. putrescine injection, its main oxidative metabolites, namely GABA, and an unidentified compound were detected in all tissues tested; inhibition of [intestinal] DAO [diamine oxidase] activity by aminoguanidine strongly suppressed formation of the 2 products.