COMPARISON OF CEREBRAL LESIONS EXPERIMENTALLY PRODUCED IN CATS BY INJECTIONS OF ALCOHOL AND OF ETOPALIN® PASTE

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Abstract
Lesions were produced in the brains of cats, using absolute alcohol and Etopalin® paste. The lesions were studied historically at intervals of 1, 6, 12, 15, and 20 weeks. Alcohol lesions were diffuse, truly neurolytic, and were surrounded by a zone of “edema” progressive throughout the period of the experiment. Etopalin® paste lesions were discrete, perhaps not truly neurolytic, but the result of tissue displacement. They were encapsulated in fibroblastic proliferation and also were enclosed in a zone of progressing “edema.” The paste became resorbed, so that reduction in size of the lesion could be anticipated. With concomitant fibrosis, the end result of the lesion should be a small contracting scar.

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