β-Ketoacyl Acyl Carrier Protein Synthase III (FabH) Is Essential for Fatty Acid Biosynthesis in Streptomyces coelicolor A3(2)
Open Access
- 1 June 2001
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 183 (11) , 3526-3530
- https://doi.org/10.1128/jb.183.11.3526-3530.2001
Abstract
The Streptomyces coelicolor fab (fatty acid biosynthesis) gene cluster ( fabD-fabH-acpP-fabF ) is cotranscribed to produce a leaderless mRNA transcript. One of these genes, fabH , encodes a ketoacyl synthase III that is essential to and is proposed to be responsible for initiation of fatty acid biosynthesis in S. coelicolor .Keywords
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