THE BINDING CHARACTERISTICS OF THE CYTOCHROME-C IRON

  • 1 October 1988
    • journal article
    • research article
    • Vol. 255  (1) , 353-356
Abstract
A comparison of the binding properties of myoglobin and cytochrome c shows that the latter, in the reduced state, has an unusually large affinity for ligands, including thioethers. This explains the outstanding stability of the methionine-iron bond of ferrous cytochrome c, and results from the intrinsic ability of the cytochrome c iron to delocalize its electrons into orbitals of the sixth axial ligand.

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