Entropy-controlled supramolecular photochirogenesis: enantiodifferentiating Z–E photoisomerization of cyclooctene included and sensitized by permethylated 6-O-benzoyl-β-cyclodextrin

Abstract
In contrast to the photosensitization with a non-methylated analogue, supramolecular photochirogenesis with a novel permethylated mono(6-O-benzoyl)-β-cyclodextrin exhibited a critical dependence of the product's enantiomeric excess upon temperature, and possessed a large differential entropy of activation (−11 J K−1 mol−1) for which the flexible host skeleton is likely to be responsible.

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