Identification of foreign gene sequences by transcript filtering against the human genome
- 14 January 2002
- journal article
- Published by Springer Nature in Nature Genetics
- Vol. 30 (2) , 141-142
- https://doi.org/10.1038/ng818
Abstract
We have developed a computational subtraction approach to detect microbial causes for putative infectious diseases by filtering a set of human tissue-derived sequences against the human genome. We demonstrate the potential of this method by identifying sequences from known pathogens in established expressed-sequence tag libraries.Keywords
This publication has 15 references indexed in Scilit:
- The Sequence of the Human GenomeScience, 2001
- Initial sequencing and analysis of the human genomeNature, 2001
- HEPATITIS BInfectious Disease Clinics of North America, 2000
- A Greedy Algorithm for Aligning DNA SequencesJournal of Computational Biology, 2000
- Human Papillomavirus Type 18: Association With Poor Prognosis in Early Stage Cervical CancerJNCI Journal of the National Cancer Institute, 1996
- Identification of Herpesvirus-Like DNA Sequences in AIDS-Sssociated Kaposi's SarcomaScience, 1994
- dbEST — database for “expressed sequence tags”Nature Genetics, 1993
- Identification of the Uncultured Bacillus of Whipple’s DiseaseNew England Journal of Medicine, 1992
- The Agent of Bacillary AngiomatosisNew England Journal of Medicine, 1990
- Basic local alignment search toolJournal of Molecular Biology, 1990