THE EFFECTS OF SYNTHETIC ANGIOTENSIN AND NORADRENALINE ON BLOOD PRESSURE AND RENAL FUNCTION

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Abstract
The effects of synthetic angiotensin II on blood pressure and renal function were investigated in a group of normal subjects and compared with those of norepinephrine. Angiotensin proved considerably more potent in raising blood pressure but was associated with a greater depression of renal function. On the other hand venospasm was less marked with angiotensin than with norepinephrine. Synthetic angiotensin II deserves further study for its use in hypotension. The decrease in renal function found in subjects with a normal pressure will require evaluation.