ANTINEUTROPHIL CYTOPLASMIC ANTIBODY-POSITIVE CRESCENTIC GLOMERULONEPHRITIS ASSOCIATED WITH ANTI-THYROID DRUG TREATMENT
- 1 November 1995
- journal article
- case report
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 34 (11) , 1090-1091
- https://doi.org/10.1093/rheumatology/34.11.1090
Abstract
Two cases of antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis following treatment with propylthiouracil and carbimazole are described. Both patients had crescentic glomerulonephritis proven by renal biopsy and responded to immunosuppressive therapy and withdrawal of the anti-thyroid drugs. Though systemic vasculitis associated with propylthiouracil is reported, this is the first report to our knowledge of renal biopsy-proven vasculitis associated with either of these drugs.Keywords
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