Amino alcohols as C-terminal protecting groups in peptide synthesis
- 31 December 1987
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 3,p. 535-539
- https://doi.org/10.1039/p19880000535
Abstract
The synthesis of peptides using amino alcohols as C-terminal protecting groups is described. C-Terminal protection of amino acid could be accomplished by reduction of the terminal carboxyl group to a hydroxymethyl group, and regeneration of the carboxyl group could be achieved by Jones' oxidation. This method was applied to the formation of di-and tripeptides.This publication has 0 references indexed in Scilit: