AN INVESTIGATION OF POLYMORPHISM IN THE INTERLEUKIN‐10 GENE PROMOTER
- 2 February 1997
- journal article
- Published by Wiley in European Journal of Immunogenetics
- Vol. 24 (1) , 1-8
- https://doi.org/10.1111/j.1365-2370.1997.tb00001.x
Abstract
Interleukin-10 (IL-10) has been described as an anti-inflammatory cytokine and B-cell proliferation factor and has been implicated in autoimmunity, tumorigenesis and transplantation tolerance. We have identified three single base pair substitutions in the IL-10 gene promoter and have investigated whether this polymorphism correlates with IL-10 protein production in vitro.Keywords
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