The C-terminal domain of human insulin degrading enzyme is required for dimerization and substrate recognition
- 19 May 2006
- journal article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 343 (4) , 1032-1037
- https://doi.org/10.1016/j.bbrc.2006.03.083
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- Twenty Years of the Alzheimer’s Disease Amyloid Hypothesis: A Genetic PerspectiveCell, 2005
- Quantitative Trait Loci Near the Insulin-Degrading Enzyme (IDE) Gene Contribute to Variation in Plasma Insulin LevelsDiabetes, 2004
- Partial Loss-of-Function Mutations in Insulin-Degrading Enzyme that Induce Diabetes also Impair Degradation of Amyloid β-ProteinThe American Journal of Pathology, 2004
- Enhanced Proteolysis of β-Amyloid in APP Transgenic Mice Prevents Plaque Formation, Secondary Pathology, and Premature DeathNeuron, 2003
- An Insulin-Degrading Enzyme Inhibitor Decreases Amylin Degradation, Increases Amylin-Induced Cytotoxicity, and Increases Amyloid Formation in Insulinoma Cell CulturesDiabetes, 2003
- Kinetics of Amyloid β-Protein Degradation Determined by Novel Fluorescence- and Fluorescence Polarization-based AssaysJournal of Biological Chemistry, 2003
- Association and Haplotype Analysis of the Insulin-Degrading Enzyme (IDE) Gene, a Strong Positional and Biological Candidate for Type 2 Diabetes SusceptibilityDiabetes, 2003
- Reduced Hippocampal Insulin-Degrading Enzyme in Late-Onset Alzheimer's Disease Is Associated with the Apolipoprotein E-ε4 AlleleThe American Journal of Pathology, 2003
- Clearing the Brain's Amyloid CobwebsNeuron, 2001
- Role of Yeast Insulin-Degrading Enzyme Homologs in Propheromone Processing and Bud Site SelectionScience, 1995