Observation of Nucleogeminy in Urinary-Sediment Cells in the Roseola-Infantum Syndrome

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Abstract
THE presence of two distinct nuclei in a majority of the epithelial cells in a urinary sediment was first observed in the course of routine urinalysis of a child with a nonspecific rash similar to that of roseola infantum and bacterial bronchopneumonia. The phenomenon of binucleated cells is here referred to as nucleogeminy. A search for further examples of the same phenomenon yielded 4 more cases, all associated with a viral exanthem. The apparent clinical diagnosis in 4 of the 5 cases was roseola infantum, and in the fifth case a diagnosis of measles had been made.This limited study . . .
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