Transient Heart Block An Unreported Toxicity of High Dose Chemotherapy With Cyclophosphamide And Etoposide

Abstract
Intensification by administration of high dose chemotherapy is increasingly used in the treatment of cancer. Serious side ellects can occur. We report a case of recurrent heart block in the hours following the administration of the drugs in a patient with small cell lung carcinoma treated by late intensive chemotherapy with etoposide and cyclophosphamide. This complication was controlled by implantation of a temporary demand pace maker.

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