Treatment of Plasma Cell Dyscrasias With Thalidomide and Its Derivatives
- 1 December 2003
- journal article
- review article
- Published by American Society of Clinical Oncology (ASCO) in Journal of Clinical Oncology
- Vol. 21 (23) , 4444-4454
- https://doi.org/10.1200/jco.2003.07.200
Abstract
Purpose: In 1999, investigators reported promising results of a phase II study of thalidomide in patients with resistant multiple myeloma (MM). Since then, various trials of thalidomide alone and in combination with other agents have been tested in patients with resistant and, more recently, untreated MM. In addition, preliminary results of phase I studies of the immunomodulatory derivatives (IMiDs) of thalidomide have been recently reported.Keywords
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