Polyamine and Magnesium Effects on Mitochondrial Respiration in Control and Heat-Acclimated Rats
- 1 January 1978
- book chapter
- Published by Springer Nature
- Vol. 32, 95-99
- https://doi.org/10.1007/978-3-0348-5559-4_10
Abstract
Studies were made of polyamine and Mg++ effects on rat liver mitochondrial α ketoglutarate oxidase (αKGO) and succinoxidase (SO). High spermidine levels suppress S3 and S4 of αKGO at 0.6–1.17 mM Mg++: some combinations of it and Mg++ increase the respiratory control ratio (RCR). Spermine suppresses S4 of αKGO and increases the RCR but suppresses the RCR of SO at high levels. In heat-acclimated (HA) animals in which we have studied only spermine effects on αKGO, RCRs of HA rats are greatly increased compared to those of controls.Keywords
This publication has 3 references indexed in Scilit:
- Polyamine effects on succinate-linked and αketoglutarate-linked rat liver mitochondrial respirationBiochemical and Biophysical Research Communications, 1977
- The Concentrations of Free and Bound Magnesium in Rat TissuesJournal of Biological Chemistry, 1973
- Effect of Transport-Inducing Antibiotics and Other Agents on Potassium Flux in Mitochondria*Biochemistry, 1967