Effect of age and chlorpromazine on memory consolidation.
- 1 June 1964
- journal article
- research article
- Published by American Psychological Association (APA) in Journal of Comparative and Physiological Psychology
- Vol. 57 (3) , 331-334
- https://doi.org/10.1037/h0047580
Abstract
Experiment 1 compares effects of chlorpromazine hydro-chloride administered to 250 rats of widely varying ages 10 sec., 30 min., 1 hr., or 2 hr. subsequent to 30 daily trials on a simple avoidance problem. When administered 1 and 2 hr. after trials, the drug impaired performance only of 30- and 600-day-old Ss. Results suggest memory consolidation is significantly longer among Ss of extreme ages. Experiment 2 compares effects of 4 distributions of trials on acquisition of conditioned avoidance responses in 30-, 120-and 600-day-old Ss. Ss of extreme ages exhibited learning decrements under massed practice conditions, presumably because of incomplete memory consolidation.Keywords
This publication has 0 references indexed in Scilit: