FAMILIAL NEPHRITIS

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Abstract
It has been known for a long time that certain disease entities have familial tendencies. Some examples of this are hemophilia, allergy, acholuric jaundice, insanity, diabetes and general arteriosclerosis and hypertension. With the exception of postscarlatinal nephritis, however, there are comparatively few recorded instances of chronic diffuse glomerular nephritis in two or more members of the same family. Dickinson1 reported a family in which for three generations many members had albuminuria. Pel2 studied the genealogical tree of a family for three generations in which there were nineteen cases of nephritis which seemed to be of a chronic interstitial type. Several of these nineteen patients died with uremia. Males and females were equally affected. All the sufferers passed the disease to the next generation with the exception of one daughter, who had six children all free from nephritis. The progeny of the nonsufferers were free from the disease. Meigs

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