Chloroquine Treatment for Malaria in Semi-Immune Patients

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Abstract
Summary For semi-immune Africans reared in districts of malarial holoendemicity in East Africa, the following single doses of chloroquine phosphate (recorded as base) are effective in the treatment of malaria caused by any species of parasite and appear to achieve radical cure of subtertian malaria: age 0 to 1 year, 19 mg; 1 to 2 years, 37 mg; 3 to 5 years, 75 mg; and 6 years and older, 120 mg. For suppression, the respective dosages are 19 mg, 37 mg, 75 mg, and 75 mg. The doses used for treatment clear parasitemia, fever and symptoms attributable to malaria as quickly as do larger doses and stimulate less vomiting. They should precede courses of suppressive treatment.

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