Abstract
The pathologic-anatomical and clinical aspects of the phyllode tumour of the breast (cystosarcoma of J. Muller) are illustrated. In order to avoid any confusion and doubt on the real nature of this neoplasm, it would be wise to reject the definition « cystosarcoma » which is still frequently employed: the term « phyllode tumour » which has the merit of establishing only the most manifest morphological character of the neoplasm is proposed. The exceptional growth is one of the peculiarities generally ascribed to this tumour; this is only partially true, for the observation of cases with moderate size are becoming more and more frequent. The essential histological picture reminds that of the intracanalicular fibroadenoma, from which it diverges, however, owing to the pseudosarcomatous aspects responsible for the wrong definition of the tumour, and to the myxoid appearance. The pseudosarcomatous aspects do not necessarily indicate, by themselves, a character of malignancy of the neoplasm; this may, therefore, be grouped among breast tumours with benign characters, as confirmed by the observation of late results in the treated cases. A correct treatment of the phyllode tumour should, therefore, be limited to the tumour exeresis, without radical removal of the breast; only in cases showing a particular tumour growth a simple mastectomy is required. The personal observation of 21 cases collected at the Cancer Institute of Milan from 1940 to 1958 has largely confirmed the remarks above reported, especially as concerns the moderate size reached by the tumours, the pseudosarcomatous aspects and the characters of absolute clinical benignity.