PLASMINOGEN ACTIVATOR PRODUCTION BY HUMAN-MONOCYTES .1. ENHANCEMENT BY ACTIVATED LYMPHOCYTES AND LYMPHOCYTE PRODUCTS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 123  (6) , 2808-2813
Abstract
Human monocytes, but not nylon wool column-non-adherent lymphocytes, produce plasminogen activator. The activity is found only in association with intact cells. Exposure of monocytes to activated lymphocytes or to lymphokine-rich supernatants enhances monocyte plasminogen activator production. The assay allows assessment of baseline and activated human monocyte function.