Glutamate and aspartate mimic the afferent transmitter in the cochlea
- 1 January 1979
- journal article
- research article
- Published by Springer Nature in Experimental Brain Research
- Vol. 34 (2) , 389-393
- https://doi.org/10.1007/bf00235683
Abstract
Glutamate (50 mM) and aspartate (50 mM) applied intracochlearly increase the spontaneous activity of ganglion cells of the auditory nerve. This activity may account for the decreased magnitude of the compound action potential observed with these substances in previous studies, and also may be additional evidence that these substances have a role in synaptic transmission between the hair cells and primary auditory afferent nerve cells.This publication has 9 references indexed in Scilit:
- Effects of Putative Transmitters on Afferent Cochlear TransmissionAnnals of Otology, Rhinology & Laryngology, 1978
- Amino acids ? Putative afferent transmitter in the cochlea?Experimental Brain Research, 1977
- Evidence that 5-HT is not the afferent transmitter in the cochleaExperimental Brain Research, 1977
- Evidence that catecholamines are not the afferent transmitter in the cochleaExperimental Brain Research, 1977
- Evidence that GABA is not the afferent transmitter in the cochleaExperimental Brain Research, 1977
- The pharmacology of transmission in the peripheral auditory system.1976
- Levels of putative transmitter amino acids in the guinea pig cochlea.Journal of Histochemistry & Cytochemistry, 1976
- Efferent innervation of vestibular and auditory receptors.Physiological Reviews, 1974
- Effects of Divalent Ions and Drugs on Synaptic Transmission in Phasic Electroreceptors in a Mormyrid FishThe Journal of general physiology, 1971