Prenatal Diagnosis of Fetal RhD Status by Molecular Analysis of Maternal Plasma
- 10 December 1998
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 339 (24) , 1734-1738
- https://doi.org/10.1056/nejm199812103392402
Abstract
The ability to determine fetal RhD status noninvasively is useful in the treatment of RhD-sensitized pregnant women whose partners are heterozygous for the RhD gene. The recent demonstration of fetal DNA in maternal plasma raises the possibility that fetal RhD genotyping may be possible with the use of maternal plasma.Keywords
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