Effects of antihistamines on isolated human lung mast cells, basophil leucocytes and erythrocytes
- 1 April 1989
- journal article
- mast cell-subtypes-and-heterogeneity
- Published by Springer Nature in Inflammation Research
- Vol. 27 (1-2) , 83-85
- https://doi.org/10.1007/bf02222205
Abstract
Low concentrations of H1- and H2-receptor directed compounds inhibited the immunologic secretion of histamine from human lung mast cells and basophil leucocytes and protected human erythrocytes from hypotonic lysis. Higher concentrations induced a release of the amine from the histaminocytes. These results are discussed in terms of the possible membrane effects of the test compounds.Keywords
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