Protein restriction in chronic renal failure.
- 1 March 1993
- journal article
- clinical trial
- Published by BMJ in Archives of Disease in Childhood
- Vol. 68 (3) , 371-375
- https://doi.org/10.1136/adc.68.3.371
Abstract
The aim of the study was to investigate the effect of a protein restricted diet on renal function and growth of children with chronic renal failure. In a multicentre prospective study 56 children (aged 2-18 years) with chronic renal failure were randomly assigned to the protein restricted (0.8-1.1 g/kg/day) or the control group. All children were followed up by the same paediatrician and dietitian. After a follow up period of three years there was no significant difference in glomerular filtration rate between children on a protein restricted diet and children of the control group. There was no significant difference in weight with respect to height and height SD score between the protein restricted and the control group. Compliance with the protein restricted diet, as indicated by the prospective diet diaries and the serum urea:creatinine ratio, was good. This study shows that children with chronic renal failure do not benefit from a protein restricted diet.Keywords
This publication has 18 references indexed in Scilit:
- Low-protein diet in children with chronic renal failure?1-year resultsPediatric Nephrology, 1991
- Prospective, randomised, multicentre trial of effect of protein restriction on progression of chronic renal insufficiencyThe Lancet, 1991
- The Effect of Protein Restriction on the Progression of Renal InsufficiencyNew England Journal of Medicine, 1989
- Chronic renal failure and growth.Archives of Disease in Childhood, 1989
- Protein Restriction in Children with Chronic Renal Failure?Blood Purification, 1989
- Effect of different levels of protein intake on renal deterioration and nutritional state in experimental renal diseaseClinical Science, 1987
- Nutritional management of children with chronic renal failurePediatric Nephrology, 1987
- Growth and development of nondialyzed children with chronic renal failure.1983
- Dietary Protein Intake and the Progressive Nature of Kidney Disease:New England Journal of Medicine, 1982
- Effect of various protein diets on growth, renal function, and survival of uremic ratsKidney International, 1979