A STRAIN OF ESCHERICHIA COLI WITH AN UNUSUALLY HIGH RATE OF AUXOTROPHIC MUTATION

Abstract
A strain of E. coli arose, apparently by mutation and accidental selection, which regularly produces auxotrophic mutants to a frequency of about 4% in any ordinary populations grown on nutrient media. This strain (ATCC11887) may serve as a useful tool in studying the causes of "spontaneous" mutation.