THE INTRAVENOUS ADMINISTRATION OF AMINO ACIDS TO DECEREBRATE AND URETHANIZED CATS

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Abstract
Cats were anesthetized and their metabolisms determined. Amino acids were then injected intravenously and the metabolic rate followed. Intravenous injection of 5 gm. of glycocoll produces a definite specific dynamic action in decerebrate cats. Glutamic acid in equal amounts produces no increase in rate of total metabolism in 3 out of 4 experiments. No increase in metabolism appears when glycocoll is injected intravenously into cats anesthetized by urethane or paraldehyde. The decerebrate preparation offers a means for further investigation of the mechanisms involved in the specific dynamic action of protein.

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