Management of prostate carcinoma. Combination of pelvic lymphadenectomy, temporary Ir-192 implantation, and external irradiation.

Abstract
Forty patients with prostate adenocarcinoma had bilateral pelvic lymphadenectomy, temporary Ir-192 implantation, and external irradiation. With the implant, the prostate received .ltoreq. 3000 rad (30 Gy) for A2 and B1 and 3500 rad (35 Gy) for B2 and C lesions in 40-45 h. Ten days to 2 wk later, 4000 rad (40 Gy) external irradiation was given in 4-5 wk using AP and PA parallel opposed fields, a box, or rotation. Patients with positive nodes were given 5000 rad (50 Gy) to the pelvis with a midline block at 4000 rad (40 Gy) so that the prostate received 7000-7500 rad (70-75 Gy). All patients were free of local recurrence. Treatment was tolerated well, with rapid regression and few complications.

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