IDENTIFICATION OF LEFT-HANDED Z-DNA BY INDIRECT IMMUNOMETHODS IN METAPHASIC CHROMOSOMES OF A MAMMAL, GERBILLUS-NIGERIAE (GERBILLIDAE, RODENTIA)
- 1 January 1982
- journal article
- research article
- Vol. 25 (4) , 218-222
Abstract
Antisera and antibodies against Z-DNA were used on metaphasic fixed chromosomes of a mammal, G. nigeriae (Gerbillidae, Rodentia). By indirect immunofluorescence and indirect immunoperoxidase labeling a heavy staining was detected in a fraction of the R-band positive heterochromatic segments, which are presumed to be rich in G-C base pairs. A weak and non homogeneous staining was also observed on euchromatic segments. The presence of a left-handed Z-DNA in mammalian chromosomes is discussed.This publication has 5 references indexed in Scilit:
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