Effects of diet and microsomal enzyme induction on the toxicity of dimethyl nitrosamine.
- 1 February 1969
- journal article
- Vol. 50 (1) , 22-5
Abstract
Feeding a protein free diet protects rats against the lethal and hepatotoxic effects of dimethyl nitrosamine. The protection cannot be reversed by starvation or by treatments which restore microsomal enzyme activity (phenobarbital or DDT). The cause of the protective effect is unknown.This publication has 3 references indexed in Scilit:
- Mechanism of Alkylation of Nucleic Acids by NitrosodimethylamineNature, 1968
- The effect of diet and 1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane (DDT) on microsomal hydroxylating enzymes and on sensitivity of rats to carbon tetrachloride poisoningBiochemical Journal, 1966
- PHENOBARBITAL-INDUCED SYNTHESIS OF THE MICROSOMAL DRUG-METABOLIZING ENZYME SYSTEM AND ITS RELATIONSHIP TO THE PROLIFERATION OF ENDOPLASMIC MEMBRANESThe Journal of cell biology, 1965