Gastric juice ammonia vs CLO test for diagnosis ofHelicobacter pylori infection

Abstract
The aim of the present study was to compare the gastric juice ammonia test to the CLO test for the diagnosis ofH. pylori infection in culture-proven cases by receiver operating characteristic (ROC) curve analysis. We studied 75 subjects (44 with chronic gastritis, 10 with gastric ulcer, 6 with duodenal ulcer, 8 with gastric cancer, and 7 normal) by endoscopy with biopsy for tissue diagnosis, culture ofH. pylori. CLO test, and by gastric juice ammonia determinations. The culture-positive group had significantly higher intragastric ammonia levels (13.7±5.8 mg/dl) than the negative group (4.9±2.4 mg/dl,PPH. pylori infection.