The problem of the precise nature of the relationship between renal disease and arterial hypertension has been brought nearer to a satisfactory solution by the work of Goldblatt and his associates.1The purpose of the present discussion is twofold: (1) to report unique clinical analogies to experimental renal hypertension and (2) to illustrate other types of somewhat unusual organic kidney disease associated with hypertension. It is hoped that this paper will stimulate the publication of more extended clinical studies on the subject of renal hypertension. Conclusions drawn from animal experiments or even from excellent pathologic studies on hypertensive patients2involve some danger of oversimplification of the problems of human hypertension. ACUTE HYPERTENSION DUE TO THROMBO-ARTERITIS OBLITERANS OF SMALL RENAL ARTERIES Case 1.—History.— F. M., a man aged 40, was admitted in January 1933 complaining of headaches, pains in the legs, loss of weight and intermittent hiccup