Allergic contact dermatitis from an organic di‐isocyanate

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Abstract
Organic di-isocyanates are used widely in industry. The concomitant respiratory complications are well-known. Cutaneous problems precipitated by skin contact with these chemicals are less well recognized. Allergic contact dermatitis caused by exposure to di-cyclohexylmethane 4,4''-di-isocyanate was demonstrated in a factory were it was used to form a surface-coating polyurethane. Attention to hygiene methods may have reduced the incidence of cases.

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