Absence of Mycobacterium tuberculosis DNA in synovial fluid from patients with rheumatoid arthritis.
Open Access
- 1 October 1994
- journal article
- research article
- Published by Elsevier in Annals of the Rheumatic Diseases
- Vol. 53 (10) , 695-698
- https://doi.org/10.1136/ard.53.10.695
Abstract
OBJECTIVES--To determine whether Mycobacterium tuberculosis DNA can be detected in synovial fluid of patients with rheumatoid arthritis (RA). METHODS--The polymerase chain reaction was applied to cellular components of synovial fluid. RESULTS--No evidence of M tuberculosis DNA was found in synovial fluid from 31 patients with RA and 13 control patients. CONCLUSION--The findings do not support a role for persistent M tuberculosis infection in the pathogenesis of RA.Keywords
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