Statins synergistically potentiate 7-hydroxystaurosporine (UCN-01) lethality in human leukemia and myeloma cells by disrupting Ras farnesylation and activation
Open Access
- 30 January 2007
- journal article
- Published by American Society of Hematology in Blood
- Vol. 109 (10) , 4415-4423
- https://doi.org/10.1182/blood-2006-09-047076
Abstract
Interactions between UCN-01 and HMG-CoA reductase inhibitors (ie, statins) have been examined in human leukemia and myeloma cells. Exposure of U937 aKeywords
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