Ependymomas Produced in Syrian Hamsters by Adenovirus 7, Strain E46 ("Hybrid" of Adenovirus 7 and SV40)
- 1 November 1965
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 120 (2) , 484-487
- https://doi.org/10.3181/00379727-120-30568
Abstract
Summary Strain E46 of adenovirus 7 produced ependymomas when inoculated intra-cerebrally in newborn hamsters. These tumors were morphologically identical to those produced by intracerebral inoculation of SV40 and unlike any tumors produced in hamsters by oncogenic adenoviruses. It has been previously shown that strain E46 is a “hybrid” virus containing the portion of the SV40 genome responsible for production of SV40 neoantigen within an adenovirus 7 capsid. The present results indicate that the “hybrid” contains that portion of the SV40 genome responsible for induction of ependymomas.This publication has 4 references indexed in Scilit:
- EVIDENCE FOR A POSSIBLE GENETIC HYBRID BETWEEN ADENOVIRUS TYPE 7 AND SV40 VIRUSESProceedings of the National Academy of Sciences, 1964
- Tumors Produced by Adenovirus 12 in Mastomys and MiceJNCI Journal of the National Cancer Institute, 1964
- Mixed Infection With Simian Virus 40 and Adenovirus 12JNCI Journal of the National Cancer Institute, 1963
- The Vacuolating Virus, S.V.40Experimental Biology and Medicine, 1960