Lipopeptide substrates for SpsB, the Staphylococcus aureus type I signal peptidase: design, conformation and conversion to α-ketoamide inhibitors
- 26 March 2003
- journal article
- Published by Elsevier in European Journal of Medicinal Chemistry
- Vol. 38 (4) , 351-356
- https://doi.org/10.1016/s0223-5234(03)00040-0
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- Discovery of Substrate for Type I Signal Peptidase SpsB fromStaphylococcus aureusJournal of Biological Chemistry, 2002
- The structure and mechanism of bacterial type I signal peptidases: A novel antibiotic targetPharmacology & Therapeutics, 2000
- Kinetic and Mechanistic Studies of Signal Peptidase I from Escherichia coliBiochemistry, 2000
- THE DESS-MARTIN PERIODINANE: 1,1,1-TRIACETOXY-1,1-DIHYDRO-1,2-BENZIODOXOL-3(1H)-ONEOrganic Syntheses, 2000
- Common protein architecture and binding sites in proteases utilizing a Ser/Lys dyad mechanismProtein Science, 1999
- Development of an Internally Quenched Fluorescent Substrate forEscherichia coliLeader PeptidaseAnalytical Biochemistry, 1998
- Molecular cloning and expression of the spsB gene encoding an essential type I signal peptidase from Staphylococcus aureusJournal of Bacteriology, 1996
- Penem inhibitors of bacterial signal peptidaseBioorganic & Medicinal Chemistry Letters, 1995
- Determination ofKm andkcat for Signal Peptidase I Using a Full Length Secretory Precursor, pro-OmpA-nuclease AJournal of Molecular Biology, 1995
- Patterns of Amino Acids near Signal‐Sequence Cleavage SitesEuropean Journal of Biochemistry, 1983