Chemoenzymatic synthesis2 of both enantiomers of fluoxetine, tomoxetine and nisoxetine: lipase-catalyzed resolution of 3-aryl-3-hydroxypropanenitriles
- 1 September 2002
- journal article
- Published by Elsevier in Tetrahedron: Asymmetry
- Vol. 13 (18) , 2039-2051
- https://doi.org/10.1016/s0957-4166(02)00537-2
Abstract
No abstract availableKeywords
This publication has 83 references indexed in Scilit:
- Ring Opening of Epoxides with Sodium Cyanide Catalyzed with Ce(OTf)4Synthetic Communications, 1999
- Novel biocatalytic reduction of aryl azides: chemoenzymatic synthesis of pyrrolo[2,1-c][1,4]benzodiazepine antibiotics1Chemical Communications, 1997
- Prozac (fluoxetine, lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: Twenty years since its first publicationLife Sciences, 1995
- Ring Opening of Epoxides with Acetone Cyanohydrin Catalyzed by Lanthanoid(III) AlkoxidesChemistry Letters, 1993
- Highly stereoselective syntheses involving N-alkyl-4,4,7.alpha.-trimethyl-trans-octahydro-1,3-benzoxazine intermediates. 2.The Journal of Organic Chemistry, 1990
- The absolute configurations and pharmacological activities of the optical isomers of fluoxetine, a selective serotonin-uptake inhibitorJournal of Medicinal Chemistry, 1988
- Organoboron compounds in organic synthesis. 4. Asymmetric aldol reactionsJournal of the American Chemical Society, 1986
- Asymmetric reduction of prochiral 3-aryl-3-oxoesters with lithium borohydride using N,N′-dibenzoylcystine as a chiral auxiliaryJournal of the Chemical Society, Chemical Communications, 1985
- C45‐ and C50‐Carotinoide. 1. Mitteilung. Synthese von (R)‐ and (S)‐LavandulolHelvetica Chimica Acta, 1982
- Lead tetraacetate and pyridine. New, mild conditions for a Hofmann-like rearrangement. New synthesis of 2-oxazolidinonesThe Journal of Organic Chemistry, 1973