Hyperimmunoglobulin E Syndrome Associated with Nephrotic Syndrome.
Open Access
- 1 January 1999
- journal article
- case report
- Published by Japanese Society of Internal Medicine in Internal Medicine
- Vol. 38 (6) , 491-494
- https://doi.org/10.2169/internalmedicine.38.491
Abstract
A 21-year-old man was admitted to Kure National Hospital with nephrotic syndrome in September 1996. He had suffered from an intractable pruritic skin rash and recurrent subcutaneous abscesses caused by the hyperimmunoglobulin E syndrome since the age of 18 months. Renal biopsy gave a diagnosis of membranoproliferative glomerulonephritis. Steroid therapy decreased urinary protein loss and hypoproteinemia, and his pruritic skin rash was improved. Patients with hyperimmunoglobulin E syndrome have a defective immune response, especially to Staphylococcus aureus infection. Continuous antigen stimulation may have caused this patient's renal histological damage as in immune complex glomerulonephritis. (Internal Medicine 38: 491-494, 1999)Keywords
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